Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11143387 | 0.85 | ALDH1A1 (0.42) | NR3C1PGRARGRM5PTGER3 | |
| SCHEMBL21872800 | 0.80 | CYP11B1 (0.48) | ARGRM5PTGER3ALDH1A1L3MBTL1 | |
| SCHEMBL13180252 | 0.78 | NR3C1 (0.42) | NR3C1PGRARGRM5PTGER3 | |
| SCHEMBL20116440 | 0.77 | LMNA (0.42) | NR3C1PGRARGRM5PTGER3 | |
| SCHEMBL30506313 | 0.77 | LMNA (0.42) | NR3C1PGRARGRM5PTGER3 | |
| SCHEMBL24826392 | 0.77 | NR3C1 (0.44) | NR3C1PGRARGRM5PTGER3 | |
| SCHEMBL13180185 | 0.77 | NPY5R (0.45) | NR3C1PGRARGRM5PTGER3 | |
| SCHEMBL5516550 | 0.77 | NR3C1 (0.41) | NR3C1PGRARGRM5PTGER3 | |
| SCHEMBL14349663 | 0.75 | NR3C1 (0.40) | NR3C1PGRARGRM5PTGER3 | |
| SCHEMBL27308881 | 0.75 | PTGER3 (0.44) | NR3C1PGRARGRM5PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019004970-A2 | HETEROBIVALENT LIGANDS SUITABLE FOR USE IN THE TREATMENT OF PARKINSON'S DISEASE | T.C. İSTANBUL MEDİPOL ÜNİVERSİTESİ (TR) | 2019-01-03 | — | — | WO | disclosed |