Styrene

Styrene

SCHEMBL2061795

C=C(C(=O)O)C(=O)OCC.C=C(C=CC#N)C(=O)OCCCC.C=Cc1ccccc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
MAPT P10636 4/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
KDM4E B2RXH2 2/20 0.36
PDCD1 Q15116 1/20 0.35
CD274 Q9NZQ7 1/20 0.35
TDP1 Q9NUW8 3/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
TSHR P16473 3/20 0.33
POLB P06746 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
HPGD P15428 1/20 0.33
APP P05067 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL251741 0.92 KDM4E (0.41) ALDH1A1MEN1KMT2AKDM4ETDP1
Styrene SCHEMBL3958178 0.89 KDM4E (0.39) ALDH1A1MAPTMEN1KMT2AKDM4E
Ethyl Fumarate SCHEMBL250291 0.88 HCAR2 (0.44) ALDH1A1MAPTMEN1KMT2AKDM4E
Styrene SCHEMBL7698100 0.88 MAPT (0.40) ALDH1A1MAPTMEN1KMT2AKDM4E
Styrene SCHEMBL8844775 0.87 KMT2A (0.48) ALDH1A1MAPTMEN1KMT2AKDM4E
Styrene SCHEMBL1449833 0.84 KDM4E (0.46) ALDH1A1MAPTMEN1KMT2AKDM4E
Styrene SCHEMBL2062109 0.83 TSHR (0.46) ALDH1A1MAPTMEN1KMT2AKDM4E
Styrene SCHEMBL2061873 0.83 TSHR (0.51) ALDH1A1MAPTMEN1KMT2AKDM4E
Styrene SCHEMBL7672043 0.83 TSHR (0.41) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL17746645 0.83 KDM4E (0.43) KDM4ETDP1L3MBTL1TSHRAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6309787-B1 ENCAPSULATING USING EMULSION POLYMERIZATION XEROX CORPORATION 2001-10-30 US claimed
EP-2172812-B1 Toner containing fluorescent nanoparticles XEROX CORP (US) 2017-05-31 EP disclosed
US-8586141-B2 Fluorescent solid ink made with fluorescent nanoparticles XEROX CORPORATION (US) 2013-11-19 US disclosed
US-8541154-B2 Toner containing fluorescent nanoparticles XEROX CORPORATION (US) 2013-09-24 US disclosed
US-8222313-B2 Radiation curable ink containing fluorescent nanoparticles XEROX CORPORATION (US) 2012-07-17 US disclosed
US-8147714-B2 Fluorescent organic nanoparticles and a process for producing fluorescent organic nanoparticles XEROX CORPORATION (US) 2012-04-03 US disclosed
US-20100086701-A1 RADIATION CURABLE INK CONTAINING FLUORESCENT NANOPARTICLES XEROX CORPORATION (US) 2010-04-08 US disclosed
US-20100086683-A1 FLUORESCENT SOLID INK MADE WITH FLUORESCENT NANOPARTICLES XEROX CORPORATION (US) 2010-04-08 US disclosed
US-20100086867-A1 TONER CONTAINING FLUORESCENT NANOPARTICLES XEROX CORPORATION (US) 2010-04-08 US disclosed
US-20100084610-A1 FLUORESCENT ORGANIC NANOPARTICLES AND A PROCESS FOR PRODUCING FLUORESCENT ORGANIC NANOPARTICLES XEROX CORPORATION (US) 2010-04-08 US disclosed
EP-2172812-A1 Toner containing fluorescent nanoparticles Xerox Corporation (US) 2010-04-07 EP disclosed
US-7571999-B2 Overcoat compositions, oil-based ink compositions, and processes for ink-jet recording using overcoat and oil-based ink compositions XEROX CORPORATION (US) 2009-08-11 US disclosed
US-20070120923-A1 Overcoat compositions, oil-based ink compositions, and processes for ink-jet recording using overcoat and oil-based ink compositions XEROX CORPORATION (US) 2007-05-31 US disclosed
EP-1640810-A1 Emulsion aggregation toner containing pigment having a small particle size Xerox Corporation (US) 2006-03-29 EP disclosed
US-20060063084-A1 Emulsion aggregation toner containing pigment having a small particle size XEROX CORPORATION (US) 2006-03-23 US disclosed
US-6447974-B1 SEMICONTINUOUS EMULSION POLYMERIZATION PROCESS FOR PREPARING TONER PARTICLES WHEREIN THE LATEX IS FORMED BY EMULSION POLYMERIZATION IN THE PRESENCE OF AN ANIONIC SURFACTANT; EXCELLENT IMAGE UNIFORMITY XEROX CORPORATION 2002-09-10 US disclosed
US-6309787-B1 ENCAPSULATING USING EMULSION POLYMERIZATION XEROX CORPORATION 2001-10-30 US disclosed
US-6294606-B1 PREPARING AQUEOUS PHASE CONTAINING ANIONIC SURFACTANT; PREPARING AN EMULSION OF MONOMERS WATER WITH ANIONIC SURFACTANT; ADDING MONOMER EMULSION TO AQUEOUS PHASE TO INITIATE SEEDING AND COMPLETING POLYMERIZATION XEROX CORPORATION 2001-09-25 US disclosed