Styrene

Styrene

SCHEMBL7698100

C=C(C(=O)O)C(=O)OCC.C=CCOC(=O)C(=C)C=CC#N.C=Cc1ccccc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.40
ALDH1A1 P00352 6/20 0.40
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
KDM4E B2RXH2 2/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
MAPK1 P28482 1/20 0.37
POLB P06746 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HPGD P15428 2/20 0.34
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34
CYP3A4 P08684 1/20 0.33
ALOX12 P18054 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PTP4A3 O75365 1/20 0.32
PTP4A1 Q93096 1/20 0.32
DHODH Q02127 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1255712 0.89 CYP3A4 (0.40) MAPTALDH1A1MEN1KMT2AKDM4E
Styrene SCHEMBL8844775 0.89 KMT2A (0.48) MAPTALDH1A1MEN1KMT2AKDM4E
Styrene SCHEMBL2061795 0.88 ALDH1A1 (0.39) MAPTALDH1A1MEN1KMT2AKDM4E
Styrene SCHEMBL327555 0.86 CYP3A4 (0.38) MAPTALDH1A1MEN1KMT2AKDM4E
Styrene SCHEMBL7696878 0.82 ALDH1A1 (0.47) MAPTALDH1A1MEN1KMT2AKDM4E
Styrene SCHEMBL7696401 0.82 MAPT (0.47) MAPTALDH1A1MEN1KMT2AKDM4E
Styrene SCHEMBL7678081 0.81 MAPT (0.58) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL17746697 0.81 CASP1 (0.41) MAPTALDH1A1MEN1KMT2AKDM4E
Styrene SCHEMBL251741 0.78 KDM4E (0.41) ALDH1A1MEN1KMT2AKDM4ELMNA
SCHEMBL7652463 0.77 ALDH1A1 (0.45) MAPTALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6413692-B1 COALESCING LATEX ENCAPSULATED COLORANT XEROX CORPORATION 2002-07-02 US claimed
US-6346358-B1 EMULSION POLYMERIZING MINIEMULSION OF MONOMER, COLORANT, IONIC SURFACTANT; ENCAPSULATION OF PIGMENT IN POLYMER SHELL; COALESCING OR FUSING OF AGGREGATES; ADDITION CO-, TER-, AND TETRAPOLYMERIZATION XEROX CORPORATION 2002-02-12 US claimed
US-6309787-B1 ENCAPSULATING USING EMULSION POLYMERIZATION XEROX CORPORATION 2001-10-30 US claimed
US-6455220-B1 AGGREGATING AND COALESCING ENCAPSULATED COLORANT IN PRESENCE OF COAGULANT, BLENDING WITH AT LEAST ONE TONER XEROX CORPORATION 2002-09-24 US disclosed
US-6413692-B1 COALESCING LATEX ENCAPSULATED COLORANT XEROX CORPORATION 2002-07-02 US disclosed
US-6346358-B1 EMULSION POLYMERIZING MINIEMULSION OF MONOMER, COLORANT, IONIC SURFACTANT; ENCAPSULATION OF PIGMENT IN POLYMER SHELL; COALESCING OR FUSING OF AGGREGATES; ADDITION CO-, TER-, AND TETRAPOLYMERIZATION XEROX CORPORATION 2002-02-12 US disclosed
US-6309787-B1 ENCAPSULATING USING EMULSION POLYMERIZATION XEROX CORPORATION 2001-10-30 US disclosed