Styrene

Styrene

SCHEMBL251741

C=C(C=CC#N)C(=O)OCCCC.C=Cc1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
TDP1 Q9NUW8 3/20 0.39
TSHR P16473 5/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
HPGD P15428 1/20 0.38
ATM Q13315 1/20 0.37
APP P05067 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
ALDH1A1 P00352 4/20 0.36
MAPK1 P28482 3/20 0.36
CYP3A4 P08684 2/20 0.36
TP53 P04637 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
BCHE P06276 4/20 0.35
ACHE P22303 3/20 0.35
LMNA P02545 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL3958178 0.97 KDM4E (0.39) KDM4ETDP1TSHRL3MBTL1HPGD
Ethyl Fumarate SCHEMBL250291 0.92 HCAR2 (0.44) KDM4ETDP1L3MBTL1ATMAPP
Styrene SCHEMBL2061795 0.92 ALDH1A1 (0.39) KDM4ETDP1TSHRL3MBTL1HPGD
Styrene SCHEMBL8844775 0.88 KMT2A (0.48) KDM4ETSHRL3MBTL1HPGDALDH1A1
SCHEMBL17746645 0.88 KDM4E (0.43) KDM4ETDP1TSHRL3MBTL1APP
Styrene SCHEMBL522764 0.85 KDM4E (0.49) KDM4ETDP1TSHRL3MBTL1APP
Styrene SCHEMBL250640 0.85 HCAR2 (0.47) KDM4ETDP1TSHRL3MBTL1HPGD
Styrene SCHEMBL251244 0.85 HCAR2 (0.38) KDM4ETDP1TSHRL3MBTL1HCAR2
SCHEMBL2259513 0.85 ATM (0.50) TDP1TSHRL3MBTL1HPGDATM
Acrylonitrile SCHEMBL295503 0.85 KDM4E (0.47) KDM4ETDP1TSHRL3MBTL1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 655 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200301296-A1 EMULSION AGGREGATION PROCESS XEROX CORPORATION 2020-09-24 US claimed
EP-3266908-B1 ANTI-BACTERIAL METALLO IONOMER POLYMER NANOCOMPOSITE FILAMENTS AND METHODS OF MAKING THE SAME XEROX CORP (US) 2020-05-06 EP claimed
US-10570290-B2 Anti-bacterial aqueous ink compositions comprising metal ion composite ionomer resins XEROX CORPORATION (US) 2020-02-25 US claimed
EP-3266613-B1 ANTI-BACTERIAL METALLO IONOMER POLYMER COMPOSITE POWDERS AND METHODS OF MAKING THE SAME XEROX CORP (US) 2019-10-16 EP claimed
US-10405540-B2 Anti-bacterial metallo ionomer polymer nanocomposite filaments and methods of making the same XEROX CORPORATION (US) 2019-09-10 US claimed
US-10113059-B2 Anti-bacterial metallo ionomer polymer nanocomposite powders and methods of making the same XEROX CORPORATION (US) 2018-10-30 US claimed
US-10067434-B2 Emulsion aggregation toners XEROX CORPORATION (US) 2018-09-04 US claimed
US-10018931-B2 Toner compositions with optimized beta-carboxyethyl acrylate shell latex for improved particle formation and morphology XEROX CORPORATION (US) 2018-07-10 US claimed
US-10007200-B2 Antimicrobial toner XEROX CORPORATION (US) 2018-06-26 US claimed
US-10007205-B2 Styrene acrylate hybrid toner process utilizing a low VOC (volatile organic compound) coalescent agent in toner shells XEROX CORPORATION (US) 2018-06-26 US claimed
US-5962179-A EXCELLENT TRIBOELECTRIC CHARGING CHARACTERISTICS AND WHICH TONERS CAN POSSESS HIGH IMAGE GLOSS, AND EXCELLENT IMAGE FIX AT LOW FUSING TEMPERATURES. XEROX CORPORATION (US) 1999-10-05 US claimed
EP-0928994-A2 Toner preparation processes Xerox Corporation (US) 1999-07-14 EP claimed
US-5869215-A Toner compositions and processes thereof XEROX CORPORATION (US) 1999-02-09 US claimed
US-5869216-A LATEX, AGGREGATION, FUSION/COALESCENCE, SURFACE TREATMENT WITH A SALICYLIC ACID OR A CATECHOL XEROX CORPORATION (US) 1999-02-09 US claimed
US-5858601-A Toner processes XEROX CORPORATION (US) 1999-01-12 US claimed
US-5827633-A Toner processes XEROX CORPORATION (US) 1998-10-27 US claimed
US-5763133-A Toner compositions and processes XEROX CORPORATION (US) 1998-06-09 US claimed
US-5747215-A Toner compositions and processes XEROX CORPORATION (US) 1998-05-05 US claimed
EP-0522233-B1 Impact resistant graft copolymers HIMONT INC (US) 1995-06-07 EP claimed
EP-0522233-A1 Impact resistant graft copolymers Himont Incorporated (US) 1993-01-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10113059-B2 Anti-bacterial metallo ionomer polymer nanocomposite powders and methods of making the same RPN1, RPN2, MSH2 KDM4E 3915/4885TDP1 3345/4885TSHR 4205/4885
US-10405540-B2 Anti-bacterial metallo ionomer polymer nanocomposite filaments and methods of making the same TERB1, NBAS, MFAP1 KDM4E 4082/4885TDP1 2803/4885TSHR 4098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.