Styrene

Styrene

SCHEMBL8844775

C=C(C=CC#N)C(=O)OCC.C=Cc1ccccc1

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.48
MEN1 O00255 4/20 0.48
ALDH1A1 P00352 9/20 0.43
MAPT P10636 7/20 0.43
POLB P06746 2/20 0.41
PDCD1 Q15116 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
NR1H4 Q96RI1 1/20 0.38
DHODH Q02127 1/20 0.38
TP53 P04637 1/20 0.38
CASP1 P29466 1/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HPGD P15428 1/20 0.38
KDM4E B2RXH2 2/20 0.37
LMNA P02545 2/20 0.37
MAPK1 P28482 1/20 0.37
RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7698100 0.89 MAPT (0.40) KMT2AMEN1ALDH1A1MAPTPOLB
Styrene SCHEMBL251741 0.88 KDM4E (0.41) KMT2AMEN1ALDH1A1TSHRTP53
Styrene SCHEMBL2061795 0.87 ALDH1A1 (0.39) KMT2AMEN1ALDH1A1MAPTPOLB
Styrene SCHEMBL1255712 0.87 CYP3A4 (0.40) KMT2AMEN1ALDH1A1MAPTTSHR
Ethyl Fumarate SCHEMBL250291 0.85 HCAR2 (0.44) KMT2AMEN1ALDH1A1MAPTSMN1; SMN2
Styrene SCHEMBL3958178 0.85 KDM4E (0.39) KMT2AMEN1ALDH1A1MAPTTSHR
Styrene SCHEMBL327555 0.84 CYP3A4 (0.38) KMT2AMEN1ALDH1A1MAPTTSHR
Styrene SCHEMBL7123463 0.84 MEN1 (0.53) KMT2AMEN1ALDH1A1MAPTPOLB
SCHEMBL2260103 0.83 ALDH1A1 (0.53) KMT2AMEN1ALDH1A1MAPTPOLB
Acrylonitrile SCHEMBL4449071 0.83 MEN1 (0.49) KMT2AMEN1ALDH1A1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5594035-A Reclamation of polymers, that contain styrene in the polymeric backbone, using a water soluble solvent based reclamation process BASF CORPORATION (US) 1997-01-14 US disclosed