⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24070907 | 0.85 | SLC6A4 (0.32) | — | |
| SCHEMBL24070903 | 0.85 | SLC6A4 (0.32) | — | |
| SCHEMBL24969102 | 0.83 | — | — | |
| SCHEMBL19525402 | 0.83 | OPRD1 (0.32) | — | |
| SCHEMBL4107789 | 0.83 | — | — | |
| SCHEMBL23967673 | 0.81 | — | — | |
| SCHEMBL15458749 | 0.81 | KISS1R (0.31) | — | |
| SCHEMBL13060790 | 0.79 | — | — | |
| SCHEMBL22401894 | 0.79 | HTR2A (0.31) | — | |
| SCHEMBL23892884 | 0.77 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4252851-A2 | EZH2 INHIBITORS FOR TREATING LYMPHOMA | Epizyme Inc (US) | 2023-10-04 | — | — | EP | disclosed |
| WO-2019002315-A1 | UV AND HEAT STABLE FLAME-RETARDANT GLASS FILLED POLYMER COMPOSITION AND REINFORCED ARTICLES THEREFROM | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-01-03 | — | — | WO | disclosed |