Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.34 |
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20619453 | 0.96 | TDO2 (0.38) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL23912101 | 0.95 | ADORA1 (0.40) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL23912068 | 0.93 | ALDH1A1 (0.37) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL20619456 | 0.93 | TDO2 (0.38) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL20619419 | 0.92 | ADORA1 (0.39) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL23912103 | 0.92 | PTGS1 (0.37) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL20619476 | 0.91 | PTGS1 (0.38) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL20619412 | 0.91 | PTGS1 (0.37) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL20619468 | 0.90 | PTGS1 (0.32) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL20619460 | 0.90 | GRM5 (0.33) | PTGS1PTGS2FEN1ADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645522-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2021-10-13 | — | — | EP | disclosed |
| WO-2019002174-A1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-01-03 | — | — | WO | disclosed |