Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20619452 | 0.96 | TDO2 (0.38) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL23912104 | 0.95 | ADORA1 (0.40) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL23912069 | 0.93 | ALDH1A1 (0.37) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL20619449 | 0.93 | TDO2 (0.38) | PTGS1PTGS2FEN1ADORA1CYP11B2 | |
| SCHEMBL20619477 | 0.91 | PTGS1 (0.38) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL20619418 | 0.91 | PTGS1 (0.37) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL20619468 | 0.90 | PTGS1 (0.32) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL20619472 | 0.90 | ADORA1 (0.37) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL20619413 | 0.89 | ADORA1 (0.37) | PTGS1PTGS2FEN1ADORA1ALDH1A1 | |
| SCHEMBL23912047 | 0.89 | SQOR (0.35) | PTGS1PTGS2FEN1ADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645522-B1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2021-10-13 | — | — | EP | disclosed |
| WO-2019002174-A1 | ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-01-03 | — | — | WO | disclosed |