SCHEMBL20619692

SCHEMBL20619692

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1cc(-c2cccnc2-c2ccccc2)cc(-n2c3ccc(C)cc3c3cc(C)ccc32)c1C#N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 6/20 0.38
ADORA2A P29274 5/20 0.38
BCHE P06276 2/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
ADORA2B P29275 1/20 0.36
LMNA P02545 4/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 5/20 0.35
ALDH1A1 P00352 3/20 0.35
HTT P42858 3/20 0.35
HSD17B10 Q99714 2/20 0.35
DHODH Q02127 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35
HPGD P15428 1/20 0.35
PPARG P37231 1/20 0.35
NCOA2 Q15596 1/20 0.35
NCOA1 Q15788 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20619695 0.97 ADORA1 (0.36) ADORA1ADORA2ABCHEPTGS1PTGS2
SCHEMBL20620055 0.94 BCHE (0.35) ADORA1ADORA2ABCHEPTGS1PTGS2
SCHEMBL23912104 0.93 ADORA1 (0.40) ADORA1ADORA2ABCHEPTGS1PTGS2
SCHEMBL20619696 0.91 ADORA1 (0.38) ADORA1ADORA2ABCHEPTGS1PTGS2
SCHEMBL23912036 0.91 BCHE (0.33) ADORA1ADORA2ABCHEPTGS1PTGS2
SCHEMBL20619690 0.91 ADORA1 (0.36) ADORA1ADORA2ABCHEPTGS1PTGS2
SCHEMBL20619413 0.89 ADORA1 (0.37) ADORA1ADORA2APTGS1PTGS2ADORA2B
SCHEMBL20619476 0.89 PTGS1 (0.38) ADORA1ADORA2APTGS1PTGS2KDM4E
SCHEMBL23912102 0.89 FEN1 (0.35) ADORA1ADORA2APTGS1PTGS2ADORA2B
SCHEMBL20619418 0.89 PTGS1 (0.37) ADORA1ADORA2APTGS1PTGS2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3645522-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-10-13 EP disclosed
WO-2019002174-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-01-03 WO disclosed