SCHEMBL23912036

SCHEMBL23912036

Cc1ccc2c(c1)c1ccccc1n2-c1cc(-c2cccnc2-c2cccc(-c3ccccc3)c2)cc(-n2c3ccccc3c3cc(C)ccc32)c1C#N

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.33
CYP11B2 P19099 1/20 0.33
ADORA2A P29274 3/20 0.33
ADORA1 P30542 3/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
PDE9A O76083 1/20 0.32
PDE1C Q14123 1/20 0.32
ELANE P08246 1/20 0.32
ACHE P22303 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
TDO2 P48775 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
PPARG P37231 1/20 0.31
NCOA2 Q15596 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20620055 0.97 BCHE (0.35) BCHEADORA2AADORA1PTGDR2ELANE
SCHEMBL20620051 0.94 CYP11B2 (0.33) BCHECYP11B2ADORA2AADORA1PDE9A
SCHEMBL20619695 0.94 ADORA1 (0.36) BCHECYP11B2ADORA2AADORA1PTGDR2
SCHEMBL20619692 0.91 ADORA1 (0.38) BCHEADORA2AADORA1ACHEKDM4E
SCHEMBL20619413 0.91 ADORA1 (0.37) CYP11B2ADORA2AADORA1PDE9APDE1C
SCHEMBL23912018 0.90 TDO2 (0.32) CYP11B2TDO2KDM4EHPGDALDH1A1
SCHEMBL23912104 0.88 ADORA1 (0.40) BCHEADORA2AADORA1PDE9APDE1C
SCHEMBL20619690 0.88 ADORA1 (0.36) BCHECYP11B2ADORA2AADORA1PDE9A
SCHEMBL23912045 0.87 ADORA2A (0.36) CYP11B2ADORA2AADORA1PDE9APDE1C
SCHEMBL20619417 0.87 ADORA1 (0.37) CYP11B2ADORA2AADORA1PDE9APDE1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3645522-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2021-10-13 EP disclosed