Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20619519 | 0.88 | NR1H4 (0.39) | NPSR1ALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL20622251 | 0.82 | L3MBTL1 (0.45) | L3MBTL1KMT2AMEN1SMN1; SMN2KCNJ1 | |
| SCHEMBL20620103 | 0.76 | AVPR2 (0.43) | L3MBTL1SMN1; SMN2STING1NPSR1ALDH1A1 | |
| SCHEMBL20622199 | 0.74 | HSD11B1 (0.41) | L3MBTL1STING1NPSR1ALDH1A1LMNA | |
| SCHEMBL20622238 | 0.73 | NOTUM (0.41) | L3MBTL1STING1NPSR1ALDH1A1LMNA | |
| SCHEMBL20620169 | 0.72 | HSD11B1 (0.40) | L3MBTL1STING1NPSR1ALDH1A1LMNA | |
| SCHEMBL20599103 | 0.71 | L3MBTL1 (0.48) | L3MBTL1KMT2AMEN1SMN1; SMN2KCNJ1 | |
| SCHEMBL17678613 | 0.71 | HPGD (0.54) | L3MBTL1KMT2AMEN1SMN1; SMN2KCNJ1 | |
| SCHEMBL20619531 | 0.70 | ALDH1A1 (0.48) | L3MBTL1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL19454363 | 0.69 | ALDH1A1 (0.42) | L3MBTL1KMT2AMEN1SMN1; SMN2KCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006295-A1 | HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |