Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29605695 | 0.79 | HIF1A (0.32) | HIF1A | |
| SCHEMBL23092070 | 0.78 | LPL (0.31) | — | |
| SCHEMBL23092074 | 0.78 | CA1 (0.36) | — | |
| SCHEMBL20599348 | 0.77 | HSP90AB1 (0.42) | HSP90AB1VCAM1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL1303608 | 0.74 | HSP90AB1 (0.32) | HSP90AB1 | |
| SCHEMBL29714911 | 0.74 | PIM1 (0.33) | DGAT1 | |
| SCHEMBL22321069 | 0.70 | — | — | |
| SCHEMBL26787616 | 0.70 | HIF1A (0.30) | HIF1A | |
| SCHEMBL15185134 | 0.70 | ALDH1A1 (0.43) | HSP90AB1HIF1AMAPTSMN1; SMN2 | |
| SCHEMBL136786 | 0.69 | GAA (0.43) | HSP90AB1HIF1AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645532-B1 | HYDROXYPHENYL PHENANTHROLINES AS POLYMERIZABLE BLOCKERS OF HIGH ENERGY LIGHT FOR PREPARING OPHTHALMIC DEVICES, SUCH AS E.G. CONTACT LENSES | JOHNSON & JOHNSON VISION CARE (US) | 2022-05-11 | — | — | EP | disclosed |
| WO-2019003064-A1 | HYDROXYPHENYL PHENANTHROLINES AS POLYMERIZABLE BLOCKERS OF HIGH ENERGY LIGHT FOR PREPARING OPHTHALMIC DEVICES, SUCH AS E.G. CONTACT LENSES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2019-01-03 | — | — | WO | disclosed |