Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22050982 | 0.84 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL20624780 | 0.83 | BTK (0.42) | BTKKMT2AHRH3SMN1; SMN2 | |
| SCHEMBL21987653 | 0.78 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL16097219 | 0.75 | CHRM2 (0.39) | BTKMAPTHRH3SMN1; SMN2 | |
| SCHEMBL7870788 | 0.70 | MAPK1 (0.38) | BTKALDH1A1MAPTHRH3SMN1; SMN2 | |
| SCHEMBL7870784 | 0.70 | MAPK1 (0.38) | BTKALDH1A1MAPTHRH3SMN1; SMN2 | |
| SCHEMBL21987420 | 0.70 | BTK (0.48) | BTKKMT2A | |
| SCHEMBL20311078 | 0.69 | CTSK (0.38) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL16118126 | 0.69 | CTSK (0.38) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL16118132 | 0.69 | CTSK (0.38) | KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019001420-A1 | HETEROARYLDIHYDROPYRIMIDINE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-03 | — | — | WO | disclosed |