Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 20/20 | 1.00 |
| ▸ | LIPC | P11150 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18219459 | 0.94 | LIPG (1.00) | LIPGLIPC | |
| SCHEMBL18219458 | 0.92 | LIPG (1.00) | LIPGLIPC | |
| SCHEMBL20603461 | 0.89 | LIPG (1.00) | LIPGLIPC | |
| SCHEMBL15464482 | 0.89 | LIPG (0.88) | LIPGLIPC | |
| SCHEMBL15465463 | 0.88 | LIPG (0.87) | LIPGLIPC | |
| SCHEMBL15464408 | 0.88 | LIPG (0.84) | LIPGLIPC | |
| SCHEMBL20625776 | 0.88 | LIPG (1.00) | LIPGLIPC | |
| SCHEMBL20625462 | 0.87 | LIPG (1.00) | LIPGLIPC | |
| SCHEMBL20603343 | 0.86 | LIPG (1.00) | LIPGLIPC | |
| SCHEMBL16899399 | 0.85 | LIPG (1.00) | LIPGLIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10173991-B2 | Sulfone amide linked benzothiazole inhibitors of endothelial lipase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10173991-B2 | Sulfone amide linked benzothiazole inhibitors of endothelial lipase | LIPG, LIPE, LPL | LIPG 1/4885LIPC 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.