SCHEMBL20625920

SCHEMBL20625920

C=C/C=c1\c(=C)n(C(=C)C=C)c2ccccc12

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.33
▸ P2RX4 Q99571 1/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24487669 0.85 POLB (0.33) POLBKDM4EMEN1ALDH1A1MAPT
SCHEMBL26306996 0.82 P2RX4 (0.33) POLBP2RX4
SCHEMBL25661154 0.82 POLB (0.38) POLBP2RX4KDM4EMEN1ALDH1A1
SCHEMBL10523214 0.77 POLB (0.47) POLBP2RX4KDM4EMEN1ALDH1A1
SCHEMBL18851741 0.74 KDM4E (0.50) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL23625525 0.73 GPR3 (0.47) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL24078148 0.71 — —
SCHEMBL29339886 0.70 HSP90AA1 (0.42) POLBKDM4EMEN1ALDH1A1MAPT
SCHEMBL9613097 0.70 KDM4E (0.44) KDM4EKMT2A
SCHEMBL25610192 0.67 MAPT (0.32) POLBMEN1MAPTRAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 — — US disclosed
US-10177316-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-01-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10177316-B2 Organic electroluminescent materials and devices OSBP, OSBPL3, OSBP2 POLB 1870/4885P2RX4 1551/4885KDM4E 4338/4885
US-20230365606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, OPRD1, OXSR1 POLB 1972/4885P2RX4 1788/4885KDM4E 4005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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