Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 8/20 | 0.41 |
| ▸ | CA2 | P00918 | 8/20 | 0.41 |
| ▸ | CA9 | Q16790 | 8/20 | 0.41 |
| ▸ | CA12 | O43570 | 7/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15952735 | 0.87 | CYP2D6 (0.50) | LMNALGALS8CYP2D6ALDH1A1MAPK1 | |
| SCHEMBL15952732 | 0.87 | CYP2D6 (0.50) | LMNALGALS8CYP2D6ALDH1A1MAPK1 | |
| SCHEMBL24086077 | 0.82 | TSHR (0.47) | LMNACYP2D6ALDH1A1MAPK1KMT2A | |
| SCHEMBL7563759 | 0.81 | LGALS8 (0.51) | LMNALGALS8CYP2D6ALDH1A1MAPK1 | |
| SCHEMBL12917696 | 0.80 | LGALS8 (0.54) | LMNALGALS8CYP2D6ALDH1A1MAPK1 | |
| SCHEMBL8328074 | 0.80 | LGALS8 (0.54) | LMNALGALS8CYP2D6ALDH1A1MAPK1 | |
| SCHEMBL970381 | 0.80 | LGALS8 (0.54) | LMNALGALS8CYP2D6ALDH1A1MAPK1 | |
| SCHEMBL8328068 | 0.80 | LGALS8 (0.54) | LMNALGALS8CYP2D6ALDH1A1MAPK1 | |
| SCHEMBL970383 | 0.80 | LGALS8 (0.54) | LMNALGALS8CYP2D6ALDH1A1MAPK1 | |
| SCHEMBL29709612 | 0.80 | LMNA (0.58) | LMNACYP2D6ALDH1A1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10174132-B2 | Heparan sulfate synthesis | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2019-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174132-B2 | Heparan sulfate synthesis | HPSE, STT3B, DDOST | LMNA 4330/4885LGALS8 168/4885CYP2D6 2403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.