Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 12/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19350865 | 0.86 | FGFR1 (0.55) | FGFR1SMN1; SMN2HPGDSRCMAPT | |
| SCHEMBL20627764 | 0.85 | FGFR1 (0.49) | FGFR1SMN1; SMN2HPGDSRCMAPT | |
| SCHEMBL14656703 | 0.85 | FGFR1 (0.64) | FGFR1SMN1; SMN2HPGDMAPTHTT | |
| SCHEMBL19350907 | 0.81 | FGFR1 (0.70) | FGFR1SMN1; SMN2SRCMAPTALDH1A1 | |
| SCHEMBL19350721 | 0.80 | SMN1; SMN2 (0.52) | FGFR1SMN1; SMN2HPGDSRCLMNA | |
| SCHEMBL25487479 | 0.80 | SMN1; SMN2 (0.47) | FGFR1SMN1; SMN2HPGDMAPTHTT | |
| SCHEMBL19350908 | 0.79 | FGFR1 (0.54) | FGFR1SMN1; SMN2HPGDSRCMAPT | |
| SCHEMBL20627046 | 0.78 | NTRK1 (0.63) | FGFR1HPGDSRCALDH1A1 | |
| SCHEMBL20627495 | 0.77 | FGFR1 (0.71) | FGFR1SRCALDH1A1NPC1RAB9A | |
| SCHEMBL20627475 | 0.76 | NPC1 (0.47) | FGFR1SMN1; SMN2HPGDMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424924-A1 | UREA COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Ancureall Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-01-09 | — | — | EP | disclosed |