Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 6/20 | 0.47 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16516620 | 0.89 | HTR1B (0.50) | MMP12HTR1AHTR1BMAPK1 | |
| SCHEMBL29776920 | 0.87 | MMP12 (0.65) | MMP12QPCTQPCTLHTR1AHTR1B | |
| SCHEMBL20627750 | 0.87 | MMP12 (0.65) | MMP12QPCTQPCTLHTR1AHTR1B | |
| SCHEMBL3162533 | 0.86 | MMP12 (0.50) | MMP12HTTLMNA | |
| SCHEMBL20627761 | 0.85 | MMP12 (0.50) | MMP12QPCTHTR1AHTR1BFGFR1 | |
| SCHEMBL8814884 | 0.81 | KDM4E (0.49) | MMP12HTR1AHTR1BFGFR1 | |
| SCHEMBL22179016 | 0.81 | MMP12 (0.41) | MMP12HTR1AHTR1BDRD2 | |
| SCHEMBL22900298 | 0.80 | MAPT (0.48) | QPCTQPCTL | |
| SCHEMBL16516348 | 0.80 | MMP12 (0.41) | MMP12HTR1AHTR1BMAPK1DRD2 | |
| SCHEMBL17916649 | 0.80 | MMP12 (0.41) | MMP12HTR1AHTR1BMAPK1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008291-B2 | Methods of forming carbene-functionalized composite materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2021-05-18 | — | — | US | disclosed |
| US-20190169132-A1 | Methods of Forming Carbene-Functionalized Composite Materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2019-06-06 | — | — | US | disclosed |
| EP-3424924-A1 | UREA COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Ancureall Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11008291-B2 | Methods of forming carbene-functionalized composite materials | VCL, CHN2, CA3 | MMP12 2908/4885QPCT 3128/4885QPCTL 3963/4885 |
| US-20190169132-A1 | Methods of Forming Carbene-Functionalized Composite Materials | VCL, CHN2, CA3 | MMP12 2908/4885QPCT 3128/4885QPCTL 3963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.