Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 12/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15057653 | 0.84 | RECQL (0.43) | RECQLPTGER1CYP1A2RAB9AADRA2A | |
| SCHEMBL20628651 | 0.84 | KMO (0.38) | PTGER1CYP1A2ALDH1A1ADRA2A | |
| SCHEMBL15057193 | 0.83 | RECQL (0.40) | RECQLPTGER1TLR8RAB9AADRA2A | |
| SCHEMBL15076168 | 0.82 | PTGER1 (0.44) | PTGER1CYP1A2ALDH1A1 | |
| SCHEMBL15057996 | 0.82 | PTGER1 (0.44) | PTGER1CYP1A2ALDH1A1 | |
| SCHEMBL15076243 | 0.81 | ALDH1A1 (0.40) | PTGER1CYP1A2ALDH1A1 | |
| SCHEMBL15057382 | 0.79 | PTGER1 (0.44) | PTGER1CYP1A2 | |
| SCHEMBL15057239 | 0.78 | PTGER1 (0.40) | PTGER1CYP1A2 | |
| SCHEMBL20628875 | 0.78 | PTGER1 (0.41) | PTGER1CYP1A2 | |
| SCHEMBL15057606 | 0.76 | PTGER1 (0.42) | PTGER1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |