Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | FOS | P01100 | 2/20 | 0.33 |
| ▸ | JUN | P05412 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15057589 | 0.84 | PLA2G4A (0.42) | PTGER1FOSJUN | |
| SCHEMBL20628633 | 0.83 | RECQL (0.43) | RECQLRAB9APTGER1TLR8ADRA2A | |
| SCHEMBL15057921 | 0.82 | FOS (0.38) | PTGER1FOSJUN | |
| SCHEMBL20628871 | 0.81 | FOS (0.37) | PTGER1FOSJUN | |
| SCHEMBL20629090 | 0.75 | FOS (0.37) | PTGER1FOSJUN | |
| SCHEMBL15057775 | 0.75 | PLA2G4A (0.43) | PTGER1FOSJUN | |
| SCHEMBL20629004 | 0.73 | PLA2G4A (0.42) | PTGER1FOSJUN | |
| SCHEMBL15057507 | 0.73 | EPHX2 (0.38) | PTGER1FOSJUN | |
| SCHEMBL22728618 | 0.73 | PTGER1 (0.39) | PTGER1 | |
| SCHEMBL20628807 | 0.71 | PTGER1 (0.37) | PTGER1HTR2AHTR2CHTR2BADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794561-A2 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013096496-A2 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2013-06-27 | — | — | WO | disclosed |