Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 16/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20628990 | 0.86 | PTGER1 (0.36) | PTGER1CYP1A2CCR5 | |
| SCHEMBL15076237 | 0.84 | PTGER1 (0.40) | PTGER1CYP1A2KMO | |
| SCHEMBL15076183 | 0.83 | PTGER1 (0.35) | PTGER1CYP1A2KMO | |
| SCHEMBL20628651 | 0.77 | KMO (0.38) | PTGER1CYP1A2KMO | |
| SCHEMBL20628789 | 0.76 | KDM4E (0.41) | PTGER1CCR5 | |
| SCHEMBL20629051 | 0.73 | CCR5 (0.33) | PTGER1CCR5 | |
| SCHEMBL15076168 | 0.69 | PTGER1 (0.44) | PTGER1CYP1A2 | |
| SCHEMBL20628877 | 0.69 | PTGER1 (0.38) | PTGER1CYP1A2 | |
| SCHEMBL15076256 | 0.69 | PTGER1 (0.44) | PTGER1CYP1A2 | |
| SCHEMBL20628633 | 0.68 | RECQL (0.43) | PTGER1CYP1A2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |