Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | THRA | P10827 | 5/20 | 0.36 |
| ▸ | THRB | P10828 | 5/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076272 | 0.93 | ELANE (0.38) | SLC22A12THRATHRBPPARDPPARG | |
| SCHEMBL15076260 | 0.84 | THRA (0.40) | SLC22A12THRATHRBPPARDPPARG | |
| SCHEMBL15057987 | 0.71 | ALKBH1 (0.39) | PPARDPPARGTP53 | |
| SCHEMBL15076194 | 0.70 | SERPINE1 (0.44) | PPARDPPARGPLA2G4AMAPT | |
| SCHEMBL15076186 | 0.70 | PTGER1 (0.43) | SLC22A12PPARDPTGER1 | |
| SCHEMBL15076284 | 0.69 | PPARG (0.44) | PPARGPLA2G4A | |
| SCHEMBL15057327 | 0.69 | PTGER1 (0.45) | PPARGPLA2G4APTGER1 | |
| SCHEMBL26581180 | 0.69 | SLC22A12 (0.53) | SLC22A12THRBPPARGMAPT | |
| SCHEMBL15076242 | 0.68 | RORC (0.45) | SLC22A12PPARGPTGER1MAPT | |
| SCHEMBL15076270 | 0.68 | NR1H4 (0.42) | PPARDPPARGPLA2G4APTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |