Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 14/20 | 0.39 |
| ▸ | ESRRA | P11474 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076249 | 0.90 | PTGER1 (0.41) | ALDH1A1MAPTPKMTSHRHTT | |
| SCHEMBL15076250 | 0.89 | PTGER1 (0.41) | ALDH1A1MAPTPKMTSHRHTT | |
| SCHEMBL20628878 | 0.83 | PTGER1 (0.40) | ALDH1A1MAPTPKMTSHRHTT | |
| SCHEMBL20628870 | 0.79 | HDAC2 (0.35) | ALDH1A1MAPTPKMTSHRHTT | |
| SCHEMBL15057237 | 0.78 | RORC (0.42) | ALDH1A1MAPTPKMTSHRHTT | |
| SCHEMBL15057366 | 0.77 | EPHX2 (0.41) | ALDH1A1MAPTPKMTSHRHTT | |
| SCHEMBL15057999 | 0.77 | HDAC2 (0.46) | MAPTESRRAEPHX2PPARGPTGDR2 | |
| SCHEMBL15057343 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTPKMTSHRHTT | |
| SCHEMBL15076165 | 0.76 | PTGER1 (0.53) | PTGER1 | |
| SCHEMBL15076168 | 0.76 | PTGER1 (0.44) | ALDH1A1MAPTPKMTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |