Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20629079 | 0.90 | PLA2G4A (0.42) | HDAC2MAPK1MAPK10PLA2G4AMAPT | |
| SCHEMBL15058053 | 0.80 | PTGER1 (0.43) | PLA2G4AKMOPTGER1 | |
| SCHEMBL15076241 | 0.80 | PLA2G4A (0.41) | PLA2G4APTGER1 | |
| SCHEMBL20629009 | 0.79 | ALDH1A1 (0.39) | ALDH1A1MAPTPKMTSHRHTT | |
| SCHEMBL15058170 | 0.78 | NLRP3 (0.44) | PTGER1MAOAMAOB | |
| SCHEMBL15076262 | 0.78 | KDM4E (0.36) | HDAC2MAPTTSHREGFRERBB2 | |
| SCHEMBL20629015 | 0.78 | PTGER1 (0.36) | PTGER1 | |
| SCHEMBL20629080 | 0.74 | MAPT (0.49) | HDAC2MAPTTSHRMAOAMAOB | |
| SCHEMBL15057888 | 0.72 | KMO (0.45) | PLA2G4AKMOPTGER1 | |
| SCHEMBL20628797 | 0.72 | KDM2B (0.42) | HDAC2PLA2G4APTGER1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |