Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 4/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076270 | 0.84 | NR1H4 (0.42) | PTGER1PTGDR2HDAC8HDAC3HDAC4 | |
| SCHEMBL15076284 | 0.79 | PPARG (0.44) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL15051963 | 0.78 | PTGDR2 (0.56) | PTGDR2CCR5ALDH1A1LMNAMAPT | |
| SCHEMBL20629016 | 0.76 | PLA2G4A (0.42) | HDAC8HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL15058239 | 0.74 | KDM4E (0.38) | PTGER1PTGDR2CCR5ALDH1A1LMNA | |
| SCHEMBL15057113 | 0.73 | PTGER1 (0.38) | PTGER1PTGDR2 | |
| SCHEMBL20629024 | 0.71 | PTGER1 (0.45) | PTGER1 | |
| SCHEMBL15052594 | 0.70 | PTGER1 (0.47) | PTGER1PTGDR2 | |
| SCHEMBL20603549 | 0.69 | PLA2G4A (0.50) | PTGER1HDAC8HDAC3HDAC4HDAC1 | |
| SCHEMBL15076247 | 0.68 | PPARG (0.47) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |