Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19790783 | 0.92 | — | — | |
| SCHEMBL3328061 | 0.79 | SHBG (0.40) | SHBGEPHX1TP53CA12CA1 | |
| Hydrochloric Acid SCHEMBL4780511 | 0.76 | EPHX1 (0.41) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL9592578 | 0.76 | SHBG (0.36) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL12913433 | 0.75 | EPHX1 (0.44) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL7143320 | 0.75 | EPHX1 (0.44) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL11606325 | 0.75 | EPHX1 (0.44) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL4589428 | 0.73 | EPHX1 (0.43) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL8917502 | 0.73 | EPHX1 (0.43) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL9141180 | 0.72 | SHBG (0.39) | SHBGEPHX1TP53CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958897-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX INC (US) | 2019-01-09 | — | — | EP | disclosed |