Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9592578 | 0.97 | SHBG (0.36) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL9592446 | 0.92 | — | — | |
| SCHEMBL4881996 | 0.85 | — | — | |
| SCHEMBL7143320 | 0.79 | EPHX1 (0.44) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL20629591 | 0.79 | SHBG (0.37) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL12913433 | 0.79 | EPHX1 (0.44) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL11606325 | 0.79 | EPHX1 (0.44) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL9141180 | 0.76 | SHBG (0.39) | SHBGEPHX1TP53CA12CA1 | |
| SCHEMBL6242702 | 0.76 | EPHX1 (0.46) | SHBGEPHX1CA12CA1CA2 | |
| SCHEMBL11145639 | 0.75 | EPHX1 (0.38) | EPHX1TP53CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995011899-A1 | PYRIMIDINE DERIVATIVES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1995-05-04 | — | — | WO | claimed |
| WO-2023212095-A1 | MOLECULES THAT ENHANCE EXTRACELLULAR VESICLE RELEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-11-02 | — | — | WO | disclosed |
| EP-3908316-A1 | TLR4-TLR7 LIGAND FORMULATIONS AS VACCINE ADJUVANTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-17 | — | — | EP | disclosed |
| WO-2020186229-A1 | TLR4-TLR7 LIGAND FORMULATIONS AS VACCINE ADJUVANTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-09-17 | — | — | WO | disclosed |
| WO-2016164640-A1 | SYNTHETIC TLR4 AND TLR7 LIGANDS TO PREVENT, INHIBIT OR TREAT LIVER DISEASE | CARSON DENNIS A (US) | 2016-10-13 | — | — | WO | disclosed |
| US-8183402-B2 | Industrial method for the synthesis of 17-acetoxy-11β[4-(dimethylamino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione and the key intermediates of the process | RICHTER GEDEON NYRT. (HU) | 2012-05-22 | — | — | US | disclosed |
| US-20100137622-A1 | INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11beta-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS | RICHTER GEDEON NYRT. (HU) | 2010-06-03 | — | — | US | disclosed |
| WO-1995011899-A1 | PYRIMIDINE DERIVATIVES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1995-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137622-A1 | INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11beta-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS | HSD17B11, HSD17B7, CYP11B1 | SHBG 29/4885EPHX1 2087/4885TP53 3677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.