Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 7/20 | 0.32 |
| ▸ | MMP9 | P14780 | 7/20 | 0.32 |
| ▸ | MMP8 | P22894 | 7/20 | 0.32 |
| ▸ | MMP13 | P45452 | 6/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20629980 | 0.79 | NR1H4 (0.36) | DGAT1NR1H4FFAR1 | |
| SCHEMBL22060200 | 0.75 | NAMPT (0.42) | DGAT1NR1H4FFAR1 | |
| SCHEMBL22059619 | 0.72 | NR1H4 (0.44) | DGAT1NR1H4FFAR1 | |
| SCHEMBL22059717 | 0.71 | NR1H4 (0.39) | DGAT1NR1H4FFAR1 | |
| SCHEMBL22059738 | 0.69 | NR1H4 (0.39) | DGAT1NR1H4FFAR1 | |
| SCHEMBL18623460 | 0.68 | L3MBTL1 (0.44) | DGAT1NR1H4FFAR1 | |
| SCHEMBL2628187 | 0.65 | KDM4E (0.41) | NR1H4 | |
| SCHEMBL13542693 | 0.64 | NAMPT (0.41) | DGAT1 | |
| SCHEMBL20630504 | 0.63 | FOLH1 (0.37) | — | |
| SCHEMBL20332148 | 0.63 | ALOX5 (0.38) | DGAT1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3650464-A1 | PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND | XDCExplorer (Shanghai) Co., Ltd. (CN) | 2020-05-13 | — | — | EP | disclosed |
| WO-2019007383-A1 | PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND | 凯惠科技发展(上海)有限公司 | 2019-01-10 | — | — | WO | disclosed |