Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 8/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | RECQL | P46063 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | MMP1 | P03956 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | APEX1 | P27695 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | SRC | P12931 | 2/20 | 0.55 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20630949 | 0.90 | POLH (0.68) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630933 | 0.88 | POLH (0.89) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630991 | 0.87 | POLH (0.77) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630770 | 0.87 | POLH (0.67) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20631318 | 0.86 | POLH (0.67) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630799 | 0.86 | POLH (0.66) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630208 | 0.85 | POLH (0.65) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630753 | 0.85 | POLH (0.64) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL17620378 | 0.84 | POLH (0.89) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL10728956 | 0.84 | POLH (1.00) | POLHMEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022118186-A1 | SENOTHERAPEUTIC COMPOUND | BIONEXA S.R.L. (IT) | 2022-06-09 | — | — | WO | disclosed |