Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 8/20 | 0.89 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.65 |
| ▸ | GAA | P10253 | 6/20 | 0.65 |
| ▸ | POLB | P06746 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.65 |
| ▸ | RECQL | P46063 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | MMP1 | P03956 | 2/20 | 0.65 |
| ▸ | APEX1 | P27695 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.59 |
| ▸ | NOX4 | Q9NPH5 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10728956 | 0.94 | POLH (1.00) | POLHKDM4EGAAPOLBMEN1 | |
| SCHEMBL20630991 | 0.91 | POLH (0.77) | POLHKDM4EGAAPOLBMEN1 | |
| SCHEMBL25304942 | 0.90 | POLH (1.00) | POLHKDM4EGAAPOLBMEN1 | |
| SCHEMBL30663836 | 0.90 | POLH (1.00) | POLHKDM4EGAAPOLBMEN1 | |
| SCHEMBL24497194 | 0.88 | POLH (0.72) | POLHKDM4EGAAPOLBMEN1 | |
| SCHEMBL25865729 | 0.86 | POLH (0.70) | POLHKDM4EGAAPOLBMEN1 | |
| SCHEMBL17620378 | 0.86 | POLH (0.89) | POLHKDM4EGAAPOLBMEN1 | |
| SCHEMBL20630949 | 0.85 | POLH (0.68) | POLHKDM4EGAAPOLBMEN1 | |
| SCHEMBL25262255 | 0.85 | POLH (1.00) | POLHKDM4EGAAPOLBMEN1 | |
| SCHEMBL20630770 | 0.85 | POLH (0.67) | POLHKDM4EGAAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200323814-A1 | MEDICAL COMPOUND | VERA SALUS RICERCA S.R.L. (IT) | 2020-10-15 | — | — | US | disclosed |
| WO-2019008537-A9 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2020-02-20 | — | — | WO | disclosed |
| WO-2019008537-A1 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2019-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200323814-A1 | MEDICAL COMPOUND | MTNR1B, CBR1, MTNR1A | POLH 3942/4885KDM4E 3339/4885GAA 3330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.