Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 2/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 2/20 | 0.30 |
| ▸ | MTTP | P55157 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631968 | 0.85 | USP2 (0.38) | CNR1NPY2R | |
| SCHEMBL20632157 | 0.85 | ABL1 (0.35) | CLK2ABL1 | |
| SCHEMBL20632665 | 0.84 | NPY2R (0.36) | NPY2RMTTP | |
| SCHEMBL20632885 | 0.81 | CYP11B2 (0.32) | CNR1 | |
| SCHEMBL20632299 | 0.79 | GSK3B (0.35) | ABL1 | |
| SCHEMBL20632764 | 0.78 | GSK3B (0.36) | ABL1 | |
| SCHEMBL20632281 | 0.77 | CHRM4 (0.35) | ABL1 | |
| SCHEMBL16249978 | 0.76 | CREBBP (0.42) | CNR1 | |
| SCHEMBL20631692 | 0.76 | SLC27A1 (0.36) | ABL1ACKR3 | |
| SCHEMBL20632516 | 0.74 | PRMT5 (0.36) | CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997029-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2019-01-09 | — | — | EP | disclosed |