Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434746 | 0.81 | FAAH (0.56) | FAAHNAAAGAAHSD17B10NPSR1 | |
| SCHEMBL11800753 | 0.79 | FAAH (0.54) | FAAHNAAAGAAHSD17B10NPSR1 | |
| SCHEMBL13913531 | 0.79 | FAAH (0.54) | FAAHNAAAGAAHSD17B10NPSR1 | |
| SCHEMBL3392525 | 0.79 | NAAA (0.74) | FAAHNAAAGAAHSD17B10NPSR1 | |
| SCHEMBL11372041 | 0.79 | FAAH (0.64) | FAAHNAAAGAAHSD17B10NPSR1 | |
| SCHEMBL4180852 | 0.79 | FAAH (0.54) | FAAHNAAAGAAHSD17B10NPSR1 | |
| SCHEMBL11191345 | 0.78 | NAAA (0.83) | FAAHNAAAGAAHSD17B10NPSR1 | |
| SCHEMBL11370007 | 0.78 | NAAA (0.77) | FAAHNAAAGAAHSD17B10NPSR1 | |
| SCHEMBL9802368 | 0.76 | FAAH (0.60) | FAAHNAAAGAAHSD17B10NPSR1 | |
| SCHEMBL9802093 | 0.76 | FAAH (0.60) | FAAHNAAAGAAHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019009370-A1 | AMIDE DERIVATIVE | 大日本住友製薬株式会社 | 2019-01-10 | — | — | WO | disclosed |