Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.60 |
| ▸ | NAAA | Q02083 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392525 | 0.84 | NAAA (0.74) | FAAHNAAAGAAHSD17B10ALDH1A1 | |
| SCHEMBL11191345 | 0.82 | NAAA (0.83) | FAAHNAAAGAAHSD17B10ALDH1A1 | |
| SCHEMBL11370007 | 0.82 | NAAA (0.77) | FAAHNAAAGAAHSD17B10ALDH1A1 | |
| SCHEMBL9802093 | 0.81 | FAAH (0.60) | FAAHNAAAGAAHSD17B10ALDH1A1 | |
| SCHEMBL10434746 | 0.78 | FAAH (0.56) | FAAHNAAAGAAHSD17B10ALDH1A1 | |
| SCHEMBL24796266 | 0.77 | GAA (0.48) | FAAHNAAAGAAHSD17B10ALDH1A1 | |
| SCHEMBL11595768 | 0.77 | FAAH (0.55) | FAAHNAAAGAAHSD17B10ALDH1A1 | |
| SCHEMBL11372041 | 0.76 | FAAH (0.64) | FAAHNAAAGAAHSD17B10ALDH1A1 | |
| SCHEMBL20633412 | 0.76 | FAAH (0.54) | FAAHNAAAGAAHSD17B10ALDH1A1 | |
| SCHEMBL4180852 | 0.76 | FAAH (0.54) | FAAHNAAAGAAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240370-B1 | N-ACYL SUBSTITUTED CYCLIC UREAS | SEQUA CORPORATION (US) | 1991-03-20 | — | — | EP | claimed |
| US-4766221-A | N-acyl substituted cyclic ureas | SEQUA CHEMICALS, INC. (US) | 1988-08-23 | — | — | US | claimed |
| EP-0240370-A2 | N-acyl substituted cyclic ureas | SEQUA CORPORATION (US) | 1987-10-07 | — | — | EP | claimed |
| EP-0240370-B1 | N-ACYL SUBSTITUTED CYCLIC UREAS | SEQUA CORPORATION (US) | 1991-03-20 | — | — | EP | disclosed |
| US-4766221-A | N-acyl substituted cyclic ureas | SEQUA CHEMICALS, INC. (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0240370-A2 | N-acyl substituted cyclic ureas | SEQUA CORPORATION (US) | 1987-10-07 | — | — | EP | disclosed |