Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.45 |
| ▸ | TTPA | P49638 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 3/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20634804 | 0.87 | GSTO1 (0.57) | GSTO1PTPN1MEN1KMT2APDE4A | |
| SCHEMBL20634802 | 0.83 | GSTO1 (0.54) | GSTO1PTPN1MEN1KMT2APDE4A | |
| SCHEMBL16077006 | 0.81 | GSTO1 (0.56) | GSTO1PTPN1MEN1KMT2APDE4A | |
| SCHEMBL20634805 | 0.80 | GSTO1 (0.51) | GSTO1PTPN1MEN1KMT2APDE4A | |
| SCHEMBL12989326 | 0.77 | MEN1 (0.53) | GSTO1PTPN1MEN1KMT2APDE4A | |
| SCHEMBL16077007 | 0.75 | PSEN1 (0.60) | GSTO1PTPN1MEN1KMT2APDE4A | |
| SCHEMBL16077014 | 0.73 | GSTO1 (0.49) | GSTO1PTPN1MEN1KMT2APDE4A | |
| SCHEMBL16260622 | 0.73 | LMNA (0.67) | GSTO1PTPN1MEN1KMT2APDE4A | |
| SCHEMBL1258674 | 0.73 | LMNA (0.67) | GSTO1PTPN1MEN1KMT2APDE4A | |
| SCHEMBL28384361 | 0.73 | LMNA (0.67) | GSTO1PTPN1MEN1KMT2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019007447-A1 | MULTIFUNCTIONAL CONJUGATES | E.P.O.S IASIS RESEARCH AND DEVELOPMENT LIMITED (CY) | 2019-01-10 | — | — | WO | disclosed |