Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23096741 | 1.00 | OPRM1 (0.46) | OPRM1ACE2SPHK1ADH1BADH1C | |
| SCHEMBL24719182 | 0.98 | OPRM1 (0.48) | OPRM1ACE2SPHK1ADH1BADH1C | |
| SCHEMBL16426479 | 0.81 | ADH1B (0.48) | OPRM1ACE2SPHK1ADH1BADH1C | |
| SCHEMBL25159563 | 0.80 | — | — | |
| SCHEMBL20922159 | 0.80 | — | — | |
| SCHEMBL14770821 | 0.80 | — | — | |
| SCHEMBL23425390 | 0.80 | ACE2 (0.47) | OPRM1ACE2SPHK1ADH1BADH1C | |
| SCHEMBL22493178 | 0.79 | ACE2 (0.45) | OPRM1ACE2SPHK1ADH1BADH1C | |
| SCHEMBL20776359 | 0.79 | ACE2 (0.45) | OPRM1ACE2SPHK1ADH1BADH1C | |
| SCHEMBL21298785 | 0.79 | ACE2 (0.45) | OPRM1ACE2SPHK1ADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2902385-B1 | DEPROTECTION METHOD FOR TETRAZOLE COMPOUND | API CORP (JP) | 2019-01-09 | — | — | EP | disclosed |