Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | HPGDS | O60760 | 4/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24006952 | 0.86 | CYP1A2 (0.33) | KDM1A | |
| SCHEMBL445603 | 0.78 | KDM1A (0.39) | KDM1AHPGDSJAK1GPR119JAK2 | |
| SCHEMBL20160685 | 0.78 | KDM1A (0.39) | KDM1AHPGDSJAK1GPR119JAK2 | |
| SCHEMBL459481 | 0.76 | GNAI3 (0.39) | KDM1AHPGDSJAK1GPR119JAK2 | |
| SCHEMBL445604 | 0.76 | KDM1A (0.38) | KDM1AHPGDSJAK1GPR119JAK2 | |
| SCHEMBL834995 | 0.76 | ACHE (0.43) | KDM1AHPGDSGPR119 | |
| SCHEMBL827042 | 0.76 | KDM1A (0.38) | KDM1AHPGDSJAK1GPR119JAK2 | |
| SCHEMBL20694070 | 0.76 | PARP1 (0.30) | PARP1 | |
| SCHEMBL1978527 | 0.76 | KDM1A (0.38) | KDM1AHPGDSJAK1GPR119JAK2 | |
| SCHEMBL25235628 | 0.76 | KDM1A (0.34) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019008025-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2019-01-10 | — | — | WO | disclosed |