Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 6/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20118722 | 0.84 | CYP3A4 (0.37) | KDM1A | |
| SCHEMBL445603 | 0.80 | KDM1A (0.39) | KDM1AJAK1JAK2TYK2JAK3 | |
| SCHEMBL18663991 | 0.79 | HTR2B (0.32) | — | |
| SCHEMBL1978527 | 0.78 | KDM1A (0.38) | KDM1AJAK1JAK2TYK2JAK3 | |
| SCHEMBL20635752 | 0.78 | KDM1A (0.38) | KDM1AJAK1JAK2TYK2JAK3 | |
| SCHEMBL834995 | 0.78 | ACHE (0.43) | KDM1AHPGDSGPR119 | |
| SCHEMBL827042 | 0.78 | KDM1A (0.38) | KDM1AJAK1JAK2TYK2JAK3 | |
| SCHEMBL445604 | 0.78 | KDM1A (0.38) | KDM1AJAK1JAK2TYK2JAK3 | |
| SCHEMBL459481 | 0.78 | GNAI3 (0.39) | KDM1AJAK1JAK2TYK2JAK3 | |
| SCHEMBL25235628 | 0.78 | KDM1A (0.34) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4115882-A1 | COMPOUNDS FOR IMPROVING MRNA SPLICING | The General Hospital Corporation (US) | 2023-01-11 | — | — | EP | disclosed |
| EP-3831822-A1 | POLYSUBSTITUTED BENZENE COMPOUND AND PREPARATION METHOD AND USE THEREOF | Suzhou Sinovent Pharmaceuticals Co., Ltd. (CN) | 2021-06-09 | — | — | EP | disclosed |
| WO-2019020041-A1 | COMPOUND AS ACC INHIBITOR AND USE THEREOF | 南京圣和药业股份有限公司 | 2019-01-31 | — | — | WO | disclosed |
| WO-2018086589-A1 | 1,5,7-TRI-SUBSTITUTED ISOQUINOLINE DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF IN MEDICINES | 上海海雁医药科技有限公司 | 2018-05-17 | — | — | WO | disclosed |