Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 4/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.38 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22433115 | 0.94 | NLRP3 (0.44) | NLRP3GSTO1 | |
| SCHEMBL20636171 | 0.93 | NLRP3 (0.47) | NLRP3GSTO1 | |
| SCHEMBL22433554 | 0.92 | NLRP3 (0.50) | NLRP3GSTO1 | |
| SCHEMBL20635800 | 0.89 | GSTO1 (0.38) | NLRP3CXCR2GSTO1 | |
| SCHEMBL20636123 | 0.88 | NLRP3 (0.45) | NLRP3GSTO1 | |
| SCHEMBL20635802 | 0.88 | NLRP3 (0.45) | NLRP3GSTO1 | |
| SCHEMBL20635808 | 0.86 | NLRP3 (0.49) | NLRP3 | |
| SCHEMBL20636167 | 0.85 | NLRP3 (0.47) | NLRP3GSTO1 | |
| SCHEMBL20635721 | 0.84 | SMN1; SMN2 (0.47) | NLRP3 | |
| SCHEMBL20634277 | 0.84 | NLRP3 (0.46) | NLRP3GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230037255-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LTD (IE) | 2023-02-02 | — | — | US | disclosed |
| US-20200291003-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | SYGNATURE DISCOVERY LIMITED (GB) | 2020-09-17 | — | — | US | disclosed |
| WO-2019008025-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2019-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291003-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | NLRP3, NOD1, NLRP1 | NLRP3 1/4885CXCR2 177/4885GSTO1 2918/4885 |
| US-20230037255-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | NLRP3, NOD1, NLRP1 | NLRP3 1/4885CXCR2 185/4885GSTO1 2734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.