Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20635668 | 0.91 | NLRP3 (0.46) | NLRP3GSTO1 | |
| SCHEMBL20636110 | 0.88 | NLRP3 (0.45) | NLRP3GSTO1 | |
| SCHEMBL22433298 | 0.86 | — | — | |
| SCHEMBL20636116 | 0.85 | GSTO1 (0.41) | NLRP3GSTO1 | |
| SCHEMBL20636165 | 0.85 | NLRP3 (0.40) | NLRP3GSTO1 | |
| SCHEMBL22433297 | 0.84 | NLRP3 (0.47) | NLRP3 | |
| SCHEMBL22433294 | 0.82 | — | — | |
| SCHEMBL20635811 | 0.82 | NLRP3 (0.45) | NLRP3GSTO1 | |
| SCHEMBL20635801 | 0.80 | MEN1 (0.46) | — | |
| SCHEMBL22433299 | 0.80 | GSTO1 (0.37) | NLRP3GSTO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019008025-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2019-01-10 | — | — | WO | disclosed |