⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20635801 | 0.93 | MEN1 (0.46) | — | |
| SCHEMBL22433562 | 0.91 | MEN1 (0.49) | — | |
| SCHEMBL20636166 | 0.89 | MEN1 (0.46) | — | |
| SCHEMBL22433299 | 0.88 | GSTO1 (0.37) | — | |
| SCHEMBL20636110 | 0.87 | NLRP3 (0.45) | — | |
| SCHEMBL22433294 | 0.86 | — | — | |
| SCHEMBL20636116 | 0.86 | GSTO1 (0.41) | — | |
| SCHEMBL20635141 | 0.85 | — | — | |
| SCHEMBL22433553 | 0.84 | NLRP3 (0.54) | — | |
| SCHEMBL22433379 | 0.82 | NLRP3 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230037255-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LTD (IE) | 2023-02-02 | — | — | US | disclosed |
| US-20200291003-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | SYGNATURE DISCOVERY LIMITED (GB) | 2020-09-17 | — | — | US | disclosed |