⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275614 | 0.78 | — | — | |
| SCHEMBL24235580 | 0.76 | HSD17B10 (0.32) | — | |
| SCHEMBL3628905 | 0.69 | LMNA (0.37) | — | |
| SCHEMBL24564924 | 0.69 | — | — | |
| SCHEMBL14535262 | 0.69 | ALDH1A1 (0.36) | — | |
| SCHEMBL283982 | 0.65 | — | — | |
| SCHEMBL218586 | 0.65 | — | — | |
| SCHEMBL95280 | 0.63 | — | — | |
| SCHEMBL649429 | 0.63 | — | — | |
| SCHEMBL10725040 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10781177-B2 | Pyridine compound and use thereof | NIPPON SODA CO., LTD. (JP) | 2020-09-22 | — | — | US | disclosed |
| US-20190071403-A1 | PYRIDINE COMPOUND AND USE THEREOF | NIPPON SODA CO., LTD. (JP) | 2019-03-07 | — | — | US | disclosed |
| EP-3428151-A1 | PYRIDINE COMPOUND AND USE THEREOF | Nippon Soda Co., Ltd. (JP) | 2019-01-16 | — | — | EP | disclosed |