SCHEMBL20640468

SCHEMBL20640468

CC(O)CCC(C)O.OCCOc1ccc(OCCO)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
RECQL P46063 1/20 0.54
NR1I2 O75469 1/20 0.53
CYP3A4 P08684 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
GAA P10253 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
MAPK1 P28482 1/20 0.44
HRH3 Q9Y5N1 1/20 0.44
LMNA P02545 1/20 0.44
RARB P10826 1/20 0.42
EPHX2 P34913 1/20 0.42
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
PDE3B Q13370 1/20 0.40
PDE3A Q14432 1/20 0.40
P2RY12 Q9H244 1/20 0.40
HTT P42858 1/20 0.40
CYP19A1 P11511 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenoxyethanol SCHEMBL28292383 0.85 ALDH1A1 (0.68) ALDH1A1RECQLNR1I2GAATDP1
SCHEMBL1129444 0.82 ADRB2 (0.50) ALDH1A1RECQLNR1I2CYP3A4SMN1; SMN2
SCHEMBL28106819 0.82 ALDH1A1 (0.75) ALDH1A1RECQLNR1I2CYP3A4SMN1; SMN2
SCHEMBL48239 0.82 ALDH1A1 (0.75) ALDH1A1RECQLNR1I2CYP3A4SMN1; SMN2
Phenoxyethanol SCHEMBL28149741 0.80 ALDH1A1 (0.73) ALDH1A1RECQLNR1I2GAATDP1
Ethylene Glycol SCHEMBL11119213 0.79 ALDH1A1 (0.71) ALDH1A1RECQLNR1I2CYP3A4SMN1; SMN2
Water SCHEMBL29229746 0.79 ALDH1A1 (0.71) ALDH1A1RECQLNR1I2CYP3A4SMN1; SMN2
SCHEMBL9270183 0.79 ALDH1A1 (0.54) ALDH1A1RECQLNR1I2CYP3A4SMN1; SMN2
SCHEMBL347372 0.79 ALDH1A1 (0.54) ALDH1A1RECQLNR1I2CYP3A4SMN1; SMN2
SCHEMBL5551011 0.79 RAB9A (0.54) ALDH1A1RECQLNR1I2CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3679093-A1 FLAME RETARDANT COMBINATIONS FOR POLYMER COMPOSITIONS AND USE THEREOF Clariant Plastics & Coatings Ltd (CH) 2020-07-15 EP disclosed
EP-3652241-A1 ADDITIVE MIXTURES FOR PLASTICS, LASER-MARKABLE POLYMER COMPOSITIONS CONTAINING SAME AND USE THEREOF Clariant Plastics & Coatings Ltd (CH) 2020-05-20 EP disclosed
WO-2019048311-A1 FLAME RETARDANT COMBINATIONS FOR POLYMER COMPOSITIONS AND USE THEREOF CLARIANT PLASTICS & COATINGS LTD (CH) 2019-03-14 WO disclosed
WO-2019011791-A1 ADDITIVE MIXTURES FOR PLASTICS, LASER-MARKABLE POLYMER COMPOSITIONS CONTAINING SAME AND USE THEREOF CLARIANT PLASTICS & COATINGS LTD (CH) 2019-01-17 WO disclosed