SCHEMBL20640475

SCHEMBL20640475

Nc1c(Cl)cc(-c2cccc3c2Cc2ccccc2-3)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.46
ACHE P22303 9/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
BCHE P06276 1/20 0.41
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
HTR7 P34969 1/20 0.38
HTR2B P41595 1/20 0.38
EGFR P00533 1/20 0.38
HSP90AA1 P07900 1/20 0.36
CASP6 P55212 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20340068 0.84 ALDH1A1 (0.46) PNMTACHENPC1RAB9AKDM4E
SCHEMBL17574466 0.84 PNMT (0.46) PNMTACHENPC1RAB9AKDM4E
SCHEMBL7805131 0.81 NPC1 (0.50) PNMTACHENPC1RAB9AKDM4E
SCHEMBL28429516 0.81 PNMT (0.46) PNMTACHENPC1RAB9AKDM4E
SCHEMBL20640814 0.81 PNMT (0.46) PNMTACHENPC1RAB9AKDM4E
SCHEMBL27759342 0.81 PNMT (0.46) PNMTACHENPC1RAB9AKDM4E
SCHEMBL17574470 0.78 ESR2 (0.49) PNMTNPC1RAB9AADORA2AADORA1
SCHEMBL27841136 0.77 ALDH1A1 (0.59) PNMTACHENPC1RAB9AKDM4E
SCHEMBL20640725 0.77 PNMT (0.43) PNMTACHENPC1RAB9AKDM4E
SCHEMBL20640668 0.77 PNMT (0.50) PNMTACHENPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110114384-B Curable composition 3M创新有限公司 2022-06-07 CN disclosed
CN-113165147-A Fast curing bonded abrasive article precursor 3M创新有限公司 2021-07-23 CN disclosed
CN-112313262-A Curable compositions and related methods 3M创新有限公司 2021-02-02 CN disclosed
EP-3652244-A1 RESIN COMPOSITION Hexcel Composites Limited (GB) 2020-05-20 EP disclosed
CN-110997748-A Curable composition comprising an epoxy resin and a curable solid filler 3M创新有限公司 2020-04-10 CN disclosed
CN-110914355-A Resin composition 赫克塞尔合成有限公司 2020-03-24 CN disclosed
WO-2019011982-A1 RESIN COMPOSITION HEXCEL COMPOSITES LIMITED (GB) 2019-01-17 WO disclosed
CN-101379111-B Polymerizable unsaturated compound and method for producing the same WAKO PURE CHEM IND LTD 2012-01-11 CN disclosed
CN-101379111-A Polymerizable unsaturated compound and method for producing the same WAKO PURE CHEM IND LTD (JP) 2009-03-04 CN disclosed