SCHEMBL28429516

SCHEMBL28429516

Nc1c(F)cc(-c2cccc3c2Cc2ccccc2-3)cc1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.46
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ACHE P22303 7/20 0.42
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
HTR7 P34969 2/20 0.38
HTR2B P41595 1/20 0.38
BCHE P06276 1/20 0.38
KDR P35968 2/20 0.38
ALOX5AP P20292 1/20 0.33
FEN1 P39748 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18335236 0.84 PNMT (0.44) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL21632772 0.84 PNMT (0.46) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL7805131 0.81 NPC1 (0.50) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL28860542 0.81 PNMT (0.44) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL27759342 0.81 PNMT (0.46) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL20640475 0.81 PNMT (0.46) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL20640814 0.81 PNMT (0.46) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL17574468 0.78 PRKAB2 (0.49) PNMTNPC1RAB9AKDM4ELMNA
SCHEMBL27821704 0.77 NPC1 (0.59) PNMTNPC1RAB9AKDM4EALDH1A1
SCHEMBL20640668 0.77 PNMT (0.50) PNMTNPC1RAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117028876-A LED filament and LED bulb lamp 嘉兴山蒲照明电器有限公司 2023-11-10 CN disclosed
CN-116891571-A Organosilicon modified polyimide resin composition and application thereof 嘉兴山蒲照明电器有限公司 2023-10-17 CN disclosed
CN-109517172-B Organosilicon modified polyimide resin composition and application thereof 嘉兴山蒲照明电器有限公司 2023-08-29 CN disclosed
CN-109973833-B LED filament and LED bulb 嘉兴山蒲照明电器有限公司 2023-03-28 CN disclosed
CN-214663776-U LED filament and LED bulb 嘉兴山蒲照明电器有限公司 2021-11-09 CN disclosed
CN-214332357-U Light-emitting diode filament and light-emitting diode bulb lamp 嘉兴山蒲照明电器有限公司 2021-10-01 CN disclosed
CN-214147468-U LED filament and LED bulb 嘉兴山蒲照明电器有限公司 2021-09-07 CN disclosed
CN-110081323-B LED filament and LED bulb JIAXING SUPER LIGHTING ELECTRIC APPLIANCE CO.,LTD. (CN) 2021-08-31 CN disclosed
CN-213629939-U Light-emitting diode filament and light-emitting diode bulb lamp 嘉兴山蒲照明电器有限公司 2021-07-06 CN disclosed
CN-213452941-U LED filament and LED bulb 嘉兴山蒲照明电器有限公司 2021-06-15 CN disclosed
CN-211952283-U LED filament and LED bulb 嘉兴山蒲照明电器有限公司 2020-11-17 CN disclosed
CN-110145698-B LED bulb lamp with organic silicon modified polyimide resin composition as filament base layer 浙江山蒲照明电器有限公司 2020-09-25 CN disclosed
CN-211475542-U LED filament and LED bulb 嘉兴山蒲照明电器有限公司 2020-09-11 CN disclosed
CN-211010831-U L ED bulb lamp 嘉兴山蒲照明电器有限公司 2020-07-14 CN disclosed