Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28897035 | 0.85 | TDP1 (0.43) | TDP1SLC6A3ERN1TYRSLC6A2 | |
| SCHEMBL2846109 | 0.83 | TYR (0.63) | MT-CO2PTGS1PTGS2TDP1ERN1 | |
| SCHEMBL1704578 | 0.83 | PTGS1 (0.52) | PTGS1PTGS2TDP1TYRPSEN1 | |
| SCHEMBL1626214 | 0.82 | SLC6A3 (0.57) | MT-CO2PTGS1PTGS2SLC6A3SLC6A2 | |
| SCHEMBL2063899 | 0.82 | MT-CO2 (0.48) | MT-CO2PTGS1PTGS2TYR | |
| SCHEMBL9063569 | 0.80 | MT-CO2 (0.55) | MT-CO2PTGS1PTGS2SLC6A3HPGD | |
| SCHEMBL17891807 | 0.80 | MT-CO2 (0.55) | MT-CO2PTGS1PTGS2TDP1SLC6A3 | |
| SCHEMBL7587589 | 0.79 | ERN1 (0.48) | MT-CO2PTGS1PTGS2TDP1ERN1 | |
| SCHEMBL10931210 | 0.78 | MT-CO2 (0.47) | MT-CO2PTGS1PTGS2TDP1SLC6A3 | |
| SCHEMBL17891802 | 0.78 | MT-CO2 (0.47) | MT-CO2PTGS1PTGS2SLC6A3PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2062884-B1 | Phenylacetic acid derivatives and pharmaceutical composition thereof | FUJI YAKUHIN CO LTD (JP) | 2013-02-20 | — | — | EP | disclosed |
| US-8148421-B2 | Phenylacetic acid derivative | FUJI YAKUHIN CO., LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20100048666-A1 | NOVEL PHENYLACETIC ACID DERIVATIVE | FUJI YAKUHIN CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2062884-A1 | NOVEL PHENYLACETIC ACID DERIVATIVE | Fuji Yakuhin Co., Ltd. (JP) | 2009-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048666-A1 | NOVEL PHENYLACETIC ACID DERIVATIVE | PTGS1, PTGER1, PTGDR | MT-CO2 1076/4885PTGS1 1/4885PTGS2 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.