Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | FABP2 | P12104 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13194591 | 0.87 | MT-CO2 (0.44) | MT-CO2PTGS2PTGS1MAOBAPP | |
| SCHEMBL2846109 | 0.83 | TYR (0.63) | MT-CO2PTGS2PTGS1MAOBTYR | |
| SCHEMBL31560842 | 0.82 | PTGS1 (0.50) | MT-CO2PTGS2PTGS1MAOBAPP | |
| SCHEMBL2064162 | 0.82 | MT-CO2 (0.48) | MT-CO2PTGS2PTGS1TYR | |
| SCHEMBL19392984 | 0.80 | MT-CO2 (0.55) | MT-CO2PTGS2PTGS1MAOBAPP | |
| SCHEMBL10967797 | 0.80 | MT-CO2 (0.55) | MT-CO2PTGS2PTGS1MAOBAPP | |
| SCHEMBL7587589 | 0.79 | ERN1 (0.48) | MT-CO2PTGS2PTGS1TSHR | |
| SCHEMBL24875457 | 0.78 | MT-CO2 (0.47) | MT-CO2PTGS2PTGS1MAOBAPP | |
| SCHEMBL13194589 | 0.78 | MT-CO2 (0.47) | MT-CO2PTGS2PTGS1MAOBAPP | |
| SCHEMBL8476208 | 0.78 | MT-CO2 (0.47) | MT-CO2PTGS2PTGS1MAOBAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2062884-B1 | Phenylacetic acid derivatives and pharmaceutical composition thereof | FUJI YAKUHIN CO LTD (JP) | 2013-02-20 | — | — | EP | disclosed |
| US-8148421-B2 | Phenylacetic acid derivative | FUJI YAKUHIN CO., LTD. (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20100048666-A1 | NOVEL PHENYLACETIC ACID DERIVATIVE | FUJI YAKUHIN CO., LTD. (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2062884-A1 | NOVEL PHENYLACETIC ACID DERIVATIVE | Fuji Yakuhin Co., Ltd. (JP) | 2009-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048666-A1 | NOVEL PHENYLACETIC ACID DERIVATIVE | PTGS1, PTGER1, PTGDR | MT-CO2 1076/4885PTGS2 7/4885PTGS1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.