Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2877401 | 0.92 | DGAT1 (0.36) | DGAT1GAAEPHX1 | |
| SCHEMBL4011681 | 0.90 | HPGD (0.30) | HPGD | |
| SCHEMBL2436431 | 0.90 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL2434403 | 0.87 | BTK (0.31) | DGAT1 | |
| SCHEMBL9554578 | 0.85 | — | — | |
| SCHEMBL6497827 | 0.83 | — | — | |
| SCHEMBL6320796 | 0.83 | BTK (0.31) | DGAT1 | |
| SCHEMBL5568399 | 0.80 | HPGD (0.32) | HPGDDGAT1GAAEPHX1CTSK | |
| SCHEMBL6608329 | 0.80 | HPGD (0.32) | HPGDDGAT1GAAEPHX1CTSK | |
| SCHEMBL5421441 | 0.78 | HPGD (0.31) | HPGDDGAT1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785625-B2 | Compound having heterocyclic ring | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2014-07-22 | — | — | US | disclosed |
| EP-2009012-B1 | NOVEL COMPOUND HAVING HETEROCYCLIC RING | RES FOUND ITSUU LAB (JP) | 2014-06-25 | — | — | EP | disclosed |
| US-20120208997-A1 | NOVEL COMPOUND HAVING HETEROCYCLIC RING | SUZUKI HIDEYUKI (JP) | 2012-08-16 | — | — | US | disclosed |
| US-8148362-B2 | Compound having heterocyclic ring | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2012-04-03 | — | — | US | disclosed |
| EP-2181994-A1 | Antimicrobial compounds | Research Foundation Itsuu Laboratory (JP) | 2010-05-05 | — | — | EP | disclosed |
| EP-2181993-A1 | Antimicrobial oxazolidinone derivatives | Research Foundation Itsuu Laboratory (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-20090299059-A1 | Novel Compound Having Heterocyclic Ring | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2009-12-03 | — | — | US | disclosed |
| EP-2009012-A1 | NOVEL COMPOUND HAVING HETEROCYCLIC RING | Research Foundation Itsuu Laboratory (JP) | 2008-12-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090299059-A1 | Novel Compound Having Heterocyclic Ring | NR0B2, NR2C2, NR0B1 | HPGD 3680/4885DGAT1 4589/4885GAA 4762/4885 |
| US-20120208997-A1 | NOVEL COMPOUND HAVING HETEROCYCLIC RING | OXA1L, MRPL21, TOP1 | HPGD 2219/4885DGAT1 4171/4885GAA 2561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.