Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2436431 | 0.98 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL2064367 | 0.92 | HPGD (0.33) | DGAT1GAAEPHX1 | |
| SCHEMBL4011681 | 0.82 | HPGD (0.30) | — | |
| SCHEMBL6497827 | 0.80 | — | — | |
| SCHEMBL2434403 | 0.80 | BTK (0.31) | DGAT1 | |
| SCHEMBL9554578 | 0.78 | — | — | |
| SCHEMBL6320796 | 0.76 | BTK (0.31) | DGAT1 | |
| SCHEMBL5568399 | 0.74 | HPGD (0.32) | DGAT1GAAEPHX1 | |
| SCHEMBL6608329 | 0.74 | HPGD (0.32) | DGAT1GAAEPHX1 | |
| SCHEMBL5421441 | 0.72 | HPGD (0.31) | DGAT1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1573068-B1 | HETEROCYCLIC FRET DYE CASSETTES FOR LABELING BIOLOGICAL MOLECULES AND THEIR USE IN DNA SEQUENCING | GE HEALTHCARE BIO SCIENCES (US) | 2010-10-20 | — | — | EP | disclosed |
| EP-1573068-A4 | HETEROCYCLIC FRET DYE CASSETTES FOR LABELING BIOLOGICAL MOLECULES AND THEIR USE IN DNA SEQUENCING | AMERSHAM BIOSCIENCES CORP (US) | 2006-01-04 | — | — | EP | disclosed |
| EP-1573068-A1 | HETEROCYCLIC FRET DYE CASSETTES FOR LABELING BIOLOGICAL MOLECULES AND THEIR USE IN DNA SEQUENCING | Amersham Biosciences Corp. (US) | 2005-09-14 | — | — | EP | disclosed |
| US-6855503-B2 | Heterocyclic FRETdye cassettes for labeling biological molecules and their use in DNA sequencing | AMERSHAM BIOSCIENCES CORP (US) | 2005-02-15 | — | — | US | disclosed |
| WO-2004059011-A1 | HETEROCYCLIC FRET DYE CASSETTES FOR LABELING BIOLOGICAL MOLECULES AND THEIR USE IN DNA SEQUENCING | AMERSHAM BIOSCIENCES CORP (US) | 2004-07-15 | — | — | WO | disclosed |
| US-20040126763-A1 | Heterocyclic FRETdye cassettes for labeling biological molecules and their use in DNA sequencing | GE HEALTHCARE BIO-SCIENCES CORP. | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040126763-A1 | Heterocyclic FRETdye cassettes for labeling biological molecules and their use in DNA sequencing | DNTT, POLL, POLRMT | DGAT1 2881/4885GAA 2857/4885EPHX1 3413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.