Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10197082 | 0.79 | PLCG1 (0.39) | PLCG1CYP1A2NOTUMMAOAHPGD | |
| SCHEMBL29844652 | 0.77 | MAOA (0.54) | CYP1A2DRD2DRD1DRD4DRD5 | |
| SCHEMBL290638 | 0.77 | MAOA (0.54) | CYP1A2DRD2DRD1DRD4DRD5 | |
| SCHEMBL29958223 | 0.77 | MAOA (0.54) | CYP1A2DRD2DRD1DRD4DRD5 | |
| SCHEMBL10159211 | 0.75 | MAOA (0.40) | PLCG1CYP1A2NOTUMMAOAHPGD | |
| Water SCHEMBL7420168 | 0.75 | MAOA (0.53) | CYP1A2DRD2DRD1DRD4DRD5 | |
| SCHEMBL9001235 | 0.74 | NOTUM (0.50) | PLCG1NOTUMMAOAHPGDGPR3 | |
| SCHEMBL18837336 | 0.71 | DRD1 (0.42) | CYP1A2DRD2DRD1DRD4DRD5 | |
| SCHEMBL10443136 | 0.69 | MAOA (0.52) | PLCG1CYP1A2NOTUMMAOAHPGD | |
| SCHEMBL18173741 | 0.69 | PLCG1 (0.65) | PLCG1NOTUMMAOAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250084091-A1 | INHIBITORS OF SARS-COV-2 | TEXAS A & M UNIV SYS (US) | 2025-03-13 | — | — | US | disclosed |
| US-20250084091-A1 | INHIBITORS OF SARS-COV-2 | TEXAS A & M UNIV SYS (US) | 2025-03-13 | — | — | US | disclosed |
| EP-4333821-A1 | INHIBITORS OF SARS-COV-2 | The Texas A&M University System (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022235813-A1 | INHIBITORS OF SARS-COV-2 | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2022-11-10 | — | — | WO | disclosed |
| EP-3256468-B1 | TRICYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO LTD (CN) | 2020-04-08 | — | — | EP | disclosed |
| US-10183917-B2 | Tricyclic compounds and uses thereof in medicine | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2019-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250084091-A1 | INHIBITORS OF SARS-COV-2 | ACE2, ACE, TMPRSS2 | PLCG1 2542/4885CYP1A2 379/4885NOTUM 758/4885 |
| US-10183917-B2 | Tricyclic compounds and uses thereof in medicine | NR1H4, SLC10A1, SLC10A2 | PLCG1 2648/4885CYP1A2 187/4885NOTUM 1258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.