Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21555511 | 0.89 | PARP10 (0.42) | PRSS1PRSS2PRSS3GPBAR1CYP1A2 | |
| SCHEMBL20644678 | 0.83 | PRSS1 (0.35) | PRSS1PRSS2PRSS3PTPRCPTPRF | |
| SCHEMBL14456158 | 0.82 | ACHE (0.46) | ACHEPRSS1PRSS2PRSS3GPBAR1 | |
| SCHEMBL14456123 | 0.82 | ACHE (0.46) | ACHEPRSS1PRSS2PRSS3GPBAR1 | |
| SCHEMBL7684912 | 0.82 | ACHE (0.55) | ACHEPTGS2ALDH1A1 | |
| SCHEMBL20644684 | 0.82 | ENPP2 (0.42) | ALDH1A1APPMAOB | |
| SCHEMBL16092506 | 0.80 | PRSS1 (0.33) | PRSS1PRSS2PRSS3PTPRCPTPRF | |
| SCHEMBL14456160 | 0.80 | ACHE (0.48) | ACHEPRSS1PRSS2PRSS3PTPRC | |
| SCHEMBL13498542 | 0.79 | ACHE (0.62) | ACHEPRSS1PRSS2PRSS3GPBAR1 | |
| SCHEMBL20990582 | 0.79 | ACHE (0.62) | ACHEPRSS1PRSS2PRSS3GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220145012-A1 | ASSOCIATIVE POLYMERS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2022-05-12 | — | — | US | disclosed |
| US-20190016859-A1 | ASSOCIATIVE POLYMERS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA | 2019-01-17 | — | — | US | disclosed |